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Abhirise 80 mg is a prescription medicine primarily used in the treatment of advanced prostate cancer. It contains Enzalutamide as its active ingredient, a powerful anti-androgen that works by blocking the effects of male hormones (androgens) like testosterone, which fuel the growth of prostate cancer cells.
Abhirise 80 mg is used in the treatment of:
Metastatic castration-resistant prostate cancer (mCRPC)
Non-metastatic castration-resistant prostate cancer
Metastatic hormone-sensitive prostate cancer (mHSPC)
Improves survival in advanced prostate cancer: Extends life expectancy in patients with late-stage or metastatic cancer.
Delays cancer progression: Slows down the spread and growth of prostate tumors.
Enhances quality of life: Helps reduce symptoms like pain and urinary problems associated with prostate cancer.
Non-invasive alternative: Offers a treatment option that can complement or delay chemotherapy or surgical castration.
Take one tablet daily or as prescribed by your doctor.
Swallow the tablet whole with a glass of water, with or without food.
Try to take the dose at the same time each day for consistent blood levels.
Do not chew, crush, or break the tablet.
If you miss a dose, take it as soon as you remember. Do not take two doses at once.
Abhirise 80 mg contains Enzalutamide, a non-steroidal anti-androgen. It works by:
Blocking androgen receptors on prostate cancer cells, preventing androgens like testosterone from binding.
Inhibiting androgen receptor signaling, which is critical for the growth and survival of prostate cancer cells.
Reducing tumor growth and delaying progression of the disease.
Unlike other hormonal therapies, enzalutamide works even in cancers that have become resistant to traditional androgen-deprivation therapy.
The standard dosage is 160 mg per day (usually taken as two 80 mg tablets).
Your doctor may adjust the dose based on your medical condition, response to treatment, and side effects.
Treatment is generally long-term and should be continued unless stopped by a doctor.
Dose adjustments may be needed in patients with liver or kidney impairment.
Store in a cool, dry place below 30°C (86°F).
Keep the medication in its original packaging to protect it from moisture and light.
Keep out of reach of children and pets.
Do not use the medicine after the expiry date printed on the pack.
Common side effects include:
Fatigue
Back pain
Hot flashes
Diarrhea
Headache
Joint pain
Less common but serious side effects:
Seizures (rare but serious)
Falls and fractures
Cognitive changes (confusion, memory issues)
Always consult a doctor if you experience any side effects, especially if they worsen or persist.
Pregnancy and Breastfeeding: Not for use in women. Avoid exposure to crushed or broken tablets.
Seizure Risk: Not recommended for patients with a history of seizures or neurological disorders.
Heart Conditions: Use with caution in patients with cardiovascular disease.
Kidney/Liver Impairment: Dosage adjustments may be necessary.
Drug Interactions: Inform your doctor about all medications, especially blood thinners, seizure medications, and drugs affecting liver enzymes.
It’s used to treat advanced stages of prostate cancer.
No, it’s a hormone therapy (anti-androgen).
No, it is strictly for men and not approved for use in women.
As long as prescribed by your doctor, often long-term.
Yes, it can be taken with or without food.
Take it as soon as possible; skip if it’s close to the next dose.
It doesn’t cure but manages and slows the progression.
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